Mazer C D, Greene M B, Misale P S, Newman D, Dorian P
Department of Anesthesia, St. Michael's Hospital, University of Toronto, Ontario, Canada.
Pacing Clin Electrophysiol. 1997 Dec;20(12 Pt 1):2930-5. doi: 10.1111/j.1540-8159.1997.tb05462.x.
Our objective was to develop a universal noninvasive method for VF induction. ICD implantation requires VF induction. Conventional rapid ventricular stimulation may fail to induce VF. Some ICDs can deliver low energy shocks on the T wave to induce VF. We hypothesized that an external dual chamber pacemaker and an external defibrillator could be configured to allow reliable VF induction with any ICD system. A surface ECG signal was delivered to the atrial channel of an external dual chamber DDD pacemaker. The 'AV' delay was adjusted so that the ventricular output of the pacemaker was delivered to an external defibrillator synchronized to deliver 5-50 J. Twenty-six patients at ICD implant or follow-up had VF induced in native rhythm (sinus rhythm or atrial fibrillation), or during a ventricular pacing train (3-8 beats at cycle length 500-880 ms). VF was successfully induced in 14 of 25 (56%) patients in native rhythm; and in 16 of 17 (94%) patients during pacing (P = 0.013). VF induction success rate was 36% in native rhythm (31/86 attempts) and 88% during pacing (69/78 attempts) (P < 0.001). The 'R' to shock interval was 269 +/- 31 ms in native rhythm and 257 +/- 48 ms during pacing. Energy delivered from the external defibrillator was 19 +/- 3 J in native rhythm and 21 +/- 6 J during pacing. We concluded that VF induction by synchronizing a small external shock to the T wave is a fast, effective way to reliably ensure arrhythmia induction with any ICD at implant or follow-up. This method is more successful during pacing than in sinus rhythm.
