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纵隔炎的治疗:早期改良Robicsek闭合术及胸大肌推进皮瓣术

Treatment of mediastinitis: early modified Robicsek closure and pectoralis major advancement flaps.

作者信息

El Gamel A, Yonan N A, Hassan R, Jones M T, Campbell C S, Deiraniya A K, Lawson R A

机构信息

Cardiothoracic Unit, Wythenshawe Hospital, Manchester, United Kingdom.

出版信息

Ann Thorac Surg. 1998 Jan;65(1):41-6; discussion 46-7. doi: 10.1016/s0003-4975(97)01063-1.

Abstract

BACKGROUND

The treatment of sternal wound complications is controversial. It is our practice to combine early aggressive debridement, a modified Robicsek sternal closure, and bilateral pectoralis major advancement flaps with or without closed irrigation in a single procedure. We reviewed our experience to determine the efficacy of this approach.

METHODS

Grade II to IV mediastinitis (dehiscence and infection) developed in 47 patients 3 to 14 days after routine open heart operations between 1990 and 1995. Culture-positive infection was identified in 60% (n = 28); 62% (n = 29) had septicemia. Thirty patients underwent incision, drainage, and surgical assessment of the wound. Once systemic signs of infection were under control (no pyrexia, normal white blood cell count), formal single-stage debridement of all infected soft tissues and bones was performed. Sternal stability was achieved using a modified Robicsek closure and bilateral pectoralis major advancement flaps. Seventeen patients were treated with staged procedures.

RESULTS

Early sternal closure and coverage with pectoralis major advancement flaps can be associated with a low mortality (0%), low morbidity (13%; n = 4: three superficial wound infections, one seroma), and shortened hospital stay (median, 22 days, compared with a median of 82 days in patients managed with conservative staged treatment; p < 0.05). Sternal stability with excellent functional and aesthetic results has been achieved in all patients.

CONCLUSIONS

The combination of aggressive early surgical debridement, sternal closure, and the placement of bilateral pectoralis major advancement flaps is a simple procedure associated with a low mortality and morbidity and a short hospital stay.

摘要

背景

胸骨伤口并发症的治疗存在争议。我们的做法是在单一手术中联合早期积极清创、改良的罗比克塞克胸骨闭合术以及双侧胸大肌推进皮瓣,可选择或不选择闭式冲洗。我们回顾了我们的经验以确定这种方法的疗效。

方法

1990年至1995年间,47例患者在常规心脏直视手术后3至14天发生了II至IV级纵隔炎(裂开和感染)。60%(n = 28)的患者被确定为培养阳性感染;62%(n = 29)的患者发生了败血症。30例患者接受了伤口的切开、引流和手术评估。一旦感染的全身症状得到控制(无发热、白细胞计数正常),对所有感染的软组织和骨骼进行正式的一期清创。使用改良的罗比克塞克闭合术和双侧胸大肌推进皮瓣实现胸骨稳定性。17例患者接受了分期手术。

结果

早期胸骨闭合和胸大肌推进皮瓣覆盖可导致低死亡率(0%)、低发病率(13%;n = 4:3例表浅伤口感染,1例血清肿)和缩短住院时间(中位数为22天,而采用保守分期治疗的患者中位数为82天;p < 0.05)。所有患者均实现了胸骨稳定性,功能和美学效果良好。

结论

积极的早期手术清创、胸骨闭合和双侧胸大肌推进皮瓣的放置相结合是一种简单的手术,具有低死亡率和发病率以及较短的住院时间。

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