一氧化氮用于先天性心脏病肺动脉高压的评估与治疗。
Nitric oxide for the evaluation and treatment of pulmonary hypertension in congenital heart disease.
作者信息
Kovalchin J P, Mott A R, Rosen K L, Feltes T F
机构信息
Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
出版信息
Tex Heart Inst J. 1997;24(4):308-16.
Abstract
The use of inhaled nitric oxide as a selective pulmonary vasodilator has expanded to include patients with congenital heart disease and pulmonary hypertension. The therapeutic and diagnostic roles of inhaled nitric oxide offer additional alternatives and benefits to these patients with pulmonary hypertension, particularly in the postoperative setting. This article reviews the background, mechanism of action, toxicities, and current clinical applications of inhaled nitric oxide in the child with congenital heart disease and pulmonary hypertension.
摘要
吸入一氧化氮作为一种选择性肺血管扩张剂的应用已扩展到包括患有先天性心脏病和肺动脉高压的患者。吸入一氧化氮的治疗和诊断作用为这些肺动脉高压患者提供了更多的选择和益处，特别是在术后环境中。本文综述了吸入一氧化氮在先天性心脏病和肺动脉高压患儿中的背景、作用机制、毒性及当前临床应用。
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Time-course and dose-response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome.一氧化氮吸入对成人呼吸窘迫综合征患者全身氧合及肺动脉高压的时间进程和剂量反应
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