Ficarra G
Institute of Stomatology, University of Florence, Italy.
Oral Dis. 1997 May;3 Suppl 1:S183-9. doi: 10.1111/j.1601-0825.1997.tb00357.x.
Oral ulcers observed during the course of HIV infection may be very severe. Such manifestations may interfere with oral functions and alter the patients' quality of life. It is important to stress that when HIV-infected individuals present with ulcerative lesions of the oral cavity, neoplastic processes and rare infections must be included in the differential diagnosis. Nontumefactive oral ulcers in HIV-positive patients may be a source of diagnostic difficulties because of the diverse array of underlying pathologic entities and multiplicity of etiologic agents. Biopsy should always be performed on long-standing ulcers, since either infection or a neoplastic process may be present. In the absence of infection or neoplasm, such lesions are then designated ulcers not otherwise specified.
在HIV感染过程中观察到的口腔溃疡可能非常严重。这些表现可能会干扰口腔功能并改变患者的生活质量。需要强调的是，当HIV感染者出现口腔溃疡性病变时，鉴别诊断必须包括肿瘤性病变和罕见感染。由于潜在病理实体的多样性和病因的多重性，HIV阳性患者的非肿瘤性口腔溃疡可能会带来诊断困难。对于长期存在的溃疡应始终进行活检，因为可能存在感染或肿瘤性病变。在没有感染或肿瘤的情况下，此类病变则被指定为未另作说明的溃疡。
