Savettieri G, Salemi G, Ragonese P, Aridon P, Scola G, Randisi G
Department of Neurological Sciences, University of Naples Federico II, Italy.
J Neurol. 1998 Jan;245(1):40-3. doi: 10.1007/s004150050172.
The prevalence and incidence of multiple sclerosis (MS) in the city of Monreale, southern Italy were ascertained 10 years after a preliminary study in the same area. The study was undertaken in a population of 26,256 people. The patients were classified according to Poser's criteria. The prevalence of MS on 31 December 1991 was 72.4 per 100,000 population. The incidence of MS for the period 1981-1991 was 3.3/100,000 per year. The mean period between onset and diagnosis of MS was 4.9 years for those patients found during this survey and 9.2 years for those in the first study. This study shows an increase of MS prevalence in Monreale city and a high incidence. The findings parallel the reduction of the lag time between onset and diagnosis.
在意大利南部蒙雷阿莱市进行的一项初步研究过去10年后，对该市多发性硬化症（MS）的患病率和发病率进行了确定。该研究针对的是26256人的人群。患者根据波泽标准进行分类。1991年12月31日MS的患病率为每10万人口72.4例。1981年至1991年期间MS的发病率为每年3.3/10万。在本次调查中发现的患者，MS发病到诊断的平均间隔时间为4.9年，而在首次研究中的患者为9.2年。本研究表明蒙雷阿莱市MS患病率上升且发病率较高。这些发现与发病到诊断之间滞后时间的缩短情况相似。
