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使用左心室辅助叶轮泵的实验性小牛的长期存活情况。

Long-term survival of experimental calves with a left ventricular assist impeller pump.

作者信息

Qian K X, Zheng M

机构信息

Institute of Biomedical Engineering, Jiangsu University of Science and Technology, Zhenjian, China.

出版信息

Med Eng Phys. 1997 Oct;19(7):675-9. doi: 10.1016/s1350-4533(96)00054-9.

Abstract

An impeller pump has been evaluated chronically in calves as a left ventricular assist device. In a group of 18 calves, three survived approx. 2 months (62, 54 and 46 days, respectively) while earlier calves survived less than 14 days. The termination of the experiments was due to bearing wear, which resulted in pump failure. The pump delivered nonpulsatile or pulsatile blood flow, according to the heart function. All the haemochemical data remained within normal or acceptable ranges during the experiments. Further improvement is now concentrated on developing a magnetic bearing to solve the problem of bearing wear.

摘要

一种叶轮泵作为左心室辅助装置已在小牛身上进行了长期评估。在一组18头小牛中,三头存活了约2个月(分别为62天、54天和46天),而早期的小牛存活时间不到14天。实验终止是由于轴承磨损,这导致了泵的故障。该泵根据心脏功能输送非搏动性或搏动性血流。在实验过程中,所有血液化学数据均保持在正常或可接受范围内。目前进一步的改进集中在开发一种磁轴承以解决轴承磨损问题。

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