Konstantinov D, Stanoeva L
Dermatologica. 1976;152(1):55-9. doi: 10.1159/000251161.
Norwegian scabies in two female homozygous twins, 12 years of age, was observed. Both children were in good psychosomatical condition. Clinical signs of Norwegian scabies with appearance of verrucous and keratotic papules on the dorsal aspect of hands, elbows and knees appeared after a year of persisting typical scabies in their family. Serum vitamin A concentration was lowered. The pathogenesis of the disease is discussed. The long-standing typical scabies is thought to be a promoting factor for manifestation of the latent and hereditary predisposition to keratotic reaction of the skin.
观察到两名12岁的女性同卵双胞胎患有挪威疥疮。两个孩子身心状况良好。在其家庭中持续出现典型疥疮一年后,出现了挪威疥疮的临床症状,在手背、肘部和膝盖背面出现疣状和角化丘疹。血清维生素A浓度降低。讨论了该病的发病机制。长期存在的典型疥疮被认为是皮肤角化反应潜在遗传易感性表现的促进因素。