Hamby R I, Aintablian A
Geriatrics. 1976 Jul;31(7):71-4.
During a five year period, idiopathic hypertrophic subaortic stenosis was diagnosed in nine patients 70 to 79 years of age and in 26 patients 20 to 66 years of age who were referred to the cardiology division of the Long Island Jewish-Hillside Medical Center because of symptomatic heart disease. Only one of the older patients, compared with 19 of the younger ones, was referred with the correct diagnosis. Coronary artery disease with papillary muscle dysfunction was incorrectly diagnosed in four of the older patients. Cardiac catheterization confirmed the diagnosis of idiopathic hypertrophic subaortic stenosis in all of the 26 younger patients and in five of the nine older ones; diagnosis was based on typical echocardiographic features in the other four patients. Symptoms, physical findings, and electrocardiographic observations were similar in both groups. Aortic valve calcification was found in one younger patient and three older ones. The ratio of women to men was higher in the older group (7:2) than in the younger group (12:14). Coronary artery disease was more frequent in the older patients (three of five, compared with six of 26). Our experience indicates that idiopathic hypertrophic subaortic stenosis is not rare during the eighth decade. The diagnosis should be considered in any patient with an unexplained appropriate heart murmur, and definitive studies, such as echocardiography, should be done. As with any condition, proper management depends on accurate diagnosis.
在五年期间,因有症状性心脏病而被转诊至长岛犹太山边医疗中心心脏病科的患者中,9例70至79岁的患者及26例20至66岁的患者被诊断为特发性肥厚性主动脉瓣下狭窄。老年患者中只有1例在转诊时被正确诊断,而年轻患者中有19例被正确诊断。4例老年患者被误诊为伴有乳头肌功能障碍的冠状动脉疾病。心脏导管检查证实所有26例年轻患者及9例老年患者中的5例患有特发性肥厚性主动脉瓣下狭窄;另外4例患者的诊断基于典型的超声心动图特征。两组患者的症状、体格检查结果及心电图表现相似。1例年轻患者及3例老年患者发现有主动脉瓣钙化。老年组中女性与男性的比例(7:2)高于年轻组(12:14)。老年患者中冠状动脉疾病更为常见(5例中有3例,而26例中有6例)。我们的经验表明,特发性肥厚性主动脉瓣下狭窄在八十岁年龄段并不罕见。对于任何有无法解释的合适心脏杂音的患者都应考虑该诊断,并应进行诸如超声心动图等确定性检查。与任何疾病一样,恰当的治疗取决于准确的诊断。