• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在加拿大进行海洛因替代治疗试验的理由。

The case for a heroin substitution treatment trial in Canada.

作者信息

Fischer B, Rehm J

机构信息

Addiction Research Foundation, Toronto, ON.

出版信息

Can J Public Health. 1997 Nov-Dec;88(6):367-70. doi: 10.1007/BF03403907.

DOI:10.1007/BF03403907
PMID:9458560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6990209/
Abstract

Illicit opiate use in Canada causes considerable harm and social cost. Methadone substitution treatment, which has been proven effective in reducing the negative effects associated with opiate use, has been used in Canada, but so far only on a small scale. Recent research suggests that, while expanding the availability of methadone substitution is certainly in the public health interest, it would not be sufficient in itself to reduce to a minimum the harms from illicit opiate use. On the basis of the epidemiology of opiate use and of related harms, and building on the experience of intervention efforts currently underway elsewhere, this paper argues for the establishment of a heroin substitution trial in Canada. Such a trial should have the goal of investigating the potential of heroin substitution to significantly reduce the health and social costs to Canadians from illicit opiate use.

摘要

在加拿大,非法使用阿片类药物造成了相当大的危害和社会成本。美沙酮替代疗法已被证明在减少与阿片类药物使用相关的负面影响方面有效,加拿大也已采用该疗法,但迄今为止规模较小。最近的研究表明,虽然扩大美沙酮替代疗法的可及性无疑符合公共卫生利益,但仅靠这一点本身并不足以将非法使用阿片类药物造成的危害降至最低。基于阿片类药物使用的流行病学情况以及相关危害,并借鉴目前其他地方正在进行的干预措施的经验,本文主张在加拿大开展海洛因替代试验。这样一项试验的目标应该是调查海洛因替代疗法在显著降低非法使用阿片类药物给加拿大人带来的健康和社会成本方面的潜力。

相似文献

1
The case for a heroin substitution treatment trial in Canada.在加拿大进行海洛因替代治疗试验的理由。
Can J Public Health. 1997 Nov-Dec;88(6):367-70. doi: 10.1007/BF03403907.
2
Heroin substitution in Canada: a necessary public health intervention?加拿大的海洛因替代疗法:一项必要的公共卫生干预措施?
Can J Public Health. 1997 Nov-Dec;88(6):365-6. doi: 10.1007/BF03403906.
3
Economic evaluation: a comparison of methadone versus buprenorphine for opiate substitution treatment.经济评估:美沙酮与丁丙诺啡用于阿片类药物替代治疗的比较
Drug Alcohol Depend. 2013 Dec 1;133(2):494-501. doi: 10.1016/j.drugalcdep.2013.07.018. Epub 2013 Aug 17.
4
Heroin-assisted treatment in Switzerland: a case study in policy change.瑞士的海洛因辅助治疗:政策变革案例研究。
Addiction. 2010 Jan;105(1):29-37. doi: 10.1111/j.1360-0443.2009.02741.x. Epub 2009 Nov 17.
5
Heroin maintenance for chronic heroin-dependent individuals.为慢性海洛因依赖者提供海洛因维持治疗。
Cochrane Database Syst Rev. 2011 Dec 7;2011(12):CD003410. doi: 10.1002/14651858.CD003410.pub4.
6
[Reimbursement of opiate substitution drugs to militaries in 2007].2007年军队阿片类替代药物报销情况
Encephale. 2012 Sep;38(4):304-9. doi: 10.1016/j.encep.2011.11.010. Epub 2012 Jan 5.
7
Methadone prescribing should continue in Scotland, says review.
BMJ. 2013 Aug 23;347:f5281. doi: 10.1136/bmj.f5281.
8
Treatment as harm reduction, defunding as harm maximization: the case of methadone maintenance.将治疗视为减少伤害,将撤资视为伤害最大化:美沙酮维持治疗的案例。
J Psychoactive Drugs. 1996 Jul-Sep;28(3):241-9. doi: 10.1080/02791072.1996.10472485.
9
Predicting biopsychosocial outcomes for heroin users in primary care treatment: a prospective longitudinal cohort study.预测初级保健治疗中海洛因使用者的心理社会结局:一项前瞻性纵向队列研究。
Br J Gen Pract. 2013 Jul;63(612):e499-505. doi: 10.3399/bjgp13X669220.
10
The Fraserburgh situation.弗雷泽堡的情况。
Br J Gen Pract. 2011 Mar;61(584):236-7. doi: 10.3399/bjgp11X561483.

引用本文的文献

1
Patterns of methadone maintenance treatment provision in Ontario: Policy success or pendulum excess?安大略省美沙酮维持治疗提供模式:政策成功还是钟摆过度?
Can Fam Physician. 2018 Feb;64(2):e95-e103.
2
Too much or never enough: a response to Treatment of opioid disorders in Canada: looking at the 'other epidemic'.要么过量,要么永远不够:对《加拿大阿片类药物障碍的治疗:审视“另一场流行病”》的回应。
Subst Abuse Treat Prev Policy. 2016 Sep 20;11(1):33. doi: 10.1186/s13011-016-0076-z.
3
How many people in Canada use prescription opioids non-medically in general and street drug using populations?加拿大有多少人在一般情况下和在使用街头毒品的人群中非医疗目的使用处方类阿片?
Can J Public Health. 2009 Mar-Apr;100(2):104-8. doi: 10.1007/BF03405516.
4
It's time for Canadian community early warning systems for illicit drug overdoses.加拿大建立非法药物过量社区早期预警系统的时候到了。
Harm Reduct J. 2007 Mar 28;4:10. doi: 10.1186/1477-7517-4-10.
5
Why we object to NAOMI. Heroin maintenance in Canada.我们为何反对娜奥米计划。加拿大的海洛因维持治疗。
Can Fam Physician. 2006 Jun;52(6):705-6, 709-11.
6
Buprenorphine: a potential new treatment option for opioid dependence.丁丙诺啡:一种治疗阿片类药物依赖的潜在新选择。
CMAJ. 2006 Jun 20;174(13):1835. doi: 10.1503/cmaj.050658.
7
Illicit opioid use in Canada: comparing social, health, and drug use characteristics of untreated users in five cities (OPICAN study).加拿大的非法阿片类药物使用情况:比较五个城市未接受治疗的使用者的社会、健康及药物使用特征(OPICAN研究)
J Urban Health. 2005 Jun;82(2):250-66. doi: 10.1093/jurban/jti049. Epub 2005 May 4.
8
Determinants of overdose incidents among illicit opioid users in 5 Canadian cities.加拿大5个城市非法阿片类药物使用者过量用药事件的决定因素。
CMAJ. 2004 Aug 3;171(3):235-9. doi: 10.1503/cmaj.1031416.
9
Social costs of untreated opioid dependence.未治疗的阿片类药物依赖的社会成本。
J Urban Health. 2000 Dec;77(4):688-722. doi: 10.1007/BF02344032.
10
Injection drug use and preventive measures: a comparison of Canadian and western European jurisdictions over time.注射吸毒与预防措施:加拿大与西欧辖区随时间的比较
CMAJ. 2000 Jun 13;162(12):1709-13.

本文引用的文献

1
Needle exchange is not enough: lessons from the Vancouver injecting drug use study.针头交换并不够:温哥华注射吸毒研究的教训
AIDS. 1997 Jul;11(8):F59-65. doi: 10.1097/00002030-199708000-00001.
2
Drugs, communities, and "harm reduction" in Germany: the new relevance of "public health" principles in local responses.
J Public Health Policy. 1995;16(4):389-411.
3
Estimating the size of a heroin-using population: an examination of the use of treatment admissions data.
Int J Addict. 1993 Jan;28(2):107-28. doi: 10.3109/10826089309039618.
4
Program changes and retention on methadone.
J Subst Abuse Treat. 1993 Nov-Dec;10(6):585-8. doi: 10.1016/0740-5472(93)90063-8.
5
The use of methadone for narcotic blockade.美沙酮用于麻醉性阻滞。
Br J Addict Alcohol Other Drugs. 1968 Sep;63(1):55-7. doi: 10.1111/j.1360-0443.1968.tb05251.x.
6
Narcotic abuse: a medical examiner's view.
N Y State J Med. 1972 Apr 1;72(7):834-40.
7
Methadone treatment of opiate dependence in Canada.加拿大美沙酮治疗阿片类药物依赖情况
Br J Addict. 1985 Sep;80(3):291-9. doi: 10.1111/j.1360-0443.1985.tb02542.x.
8
Relapse to use of heroin, cocaine, and other drugs in the first year after treatment.治疗后第一年出现海洛因、可卡因及其他药物复吸的情况。
NIDA Res Monogr. 1986;72:157-66.
9
Medical safety and side effects of methadone in tolerant individuals.
J Psychoactive Drugs. 1991 Apr-Jun;23(2):6 pages following 232.