Schmidt M H, Göpel C, Blanz B
Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters am Zentralinstitut für Seelische Gesundheit Mannheim.
Z Kinder Jugendpsychiatr Psychother. 1997 Aug;25(3):160-7.
Improvement in cognitive functions with weight gain in patients with anorexia nervosa leads to the assumption of cognitive functions decrease during long-lasting self-starvation. In the present study the effects of chronic undernutrition on learning abilities, in rodents were investigated in an open-field test and a passive avoidance paradigm. The findings suggest that cognitive deficits after a weight loss of 32% of normal weight may be caused by undernutrition. Further research is necessary to clarify other influencing conditions and identify the underlying biochemical mechanisms.
神经性厌食症患者体重增加时认知功能改善，这导致人们认为长期自我饥饿期间认知功能会下降。在本研究中，通过旷场试验和被动回避范式研究了慢性营养不良对啮齿动物学习能力的影响。研究结果表明，体重减轻至正常体重的32%后的认知缺陷可能是由营养不良引起的。有必要进行进一步研究以阐明其他影响因素并确定潜在的生化机制。
