心脏线粒体中镁离子的呼吸依赖性外流。
Respiration-dependent efflux of magnesium ions from heart mitochondria.
作者信息
Crompton M, Capano M, Carafoli E
出版信息
Biochem J. 1976 Mar 15;154(3):735-42. doi: 10.1042/bj1540735.
Abstract
Energy-linked respiration causes a net movement of Mg2+ between rat heart mitochondria and the ambient medium. When the extramitochondrial concontration of Mg2+ is less that about 2.5 mM the net movement of Mg2+ constitutes an efflux, whereas a net influx of Mg2+ occurs when the external concentration of Mg2+ is greater than this. Both the efflux and the influx are induced to only a very small degree by externally added ATP. Evidence suggests that Pi may be required for the respiration-induced efflux of Mg2+.
摘要
能量关联呼吸作用导致镁离子在大鼠心脏线粒体与周围介质之间的净移动。当线粒体外镁离子浓度低于约2.5 mM时，镁离子的净移动构成外流，而当外部镁离子浓度高于此值时，则会发生镁离子的净内流。外流和内流仅在非常小的程度上由外部添加的ATP诱导。有证据表明，呼吸作用诱导的镁离子外流可能需要无机磷酸（Pi）。
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