痴呆症药物的热门与冷门。第二部分。
What's hot, what's not, in dementia drugs. Part II.
作者信息
Buckwalter K C
机构信息
University of Iowa, College of Nursing, Iowa City 52242, USA.
出版信息
J Gerontol Nurs. 1997 Dec;23(12):46-7. doi: 10.3928/0098-9134-19971201-11.
Research is dramatically increasing our understanding of what goes awry in the brains of persons with AD. Three compounds approved for use in other conditions, estrogen, anti-inflammatory drugs, and antioxidants, are currently under study based on their ability to promote cell metabolism and survival, counteract inflammatory responses, and protect neurons from oxidative damage. All three show promise in terms of treating and possibly preventing Alzheimer's disease.
研究正在极大地增进我们对阿尔茨海默病患者大脑中出现问题的理解。三种已被批准用于其他病症的化合物，即雌激素、抗炎药物和抗氧化剂，目前正在基于它们促进细胞代谢和存活、对抗炎症反应以及保护神经元免受氧化损伤的能力进行研究。这三种化合物在治疗甚至可能预防阿尔茨海默病方面都显示出了前景。
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