Wenisch S, Jöst K, Hummel G
Institut für Veterinär, Universität Giessen, Deutschland.
Anat Histol Embryol. 1997 Dec;26(4):281-7. doi: 10.1111/j.1439-0264.1997.tb00137.x.
Based upon macroscopic and light microscopic examinations the development of the superior colliculus of bovine embryos and fetuses with crown-rump lengths (CRL) ranging from 0.8 to 90.0 cm was studied. Macroscopically, the mesencephalon can be recognized for the first time at 0.8 cm CRL, whereas the superior colliculus can be clearly differentiated in embryos of 4.5 cm CRL. The macroscopic features of this brain area have reached adult conditions at 80.0 cm CRL. The light microscopic examination reflected the beginning of layer formation at 0.8 cm CRL, which is induced by the proliferating activity of the ventricular zone. Up to 3.4 cm CRL the primordium of the tectum opticum exhibits still a trilaminate pattern (ventricular-intermediate- and marginal zone), but at 4.5 cm CRL, the formation of the specific tectal layers is marked by the origin of the stratum profundum and intermedium. With the appearance of the tenth layer named stratum opticum at 8.0 cm CRL the laminar pattern corresponds to the characteristics of adult animals.
基于大体和光学显微镜检查,对冠臀长(CRL)在0.8至90.0厘米之间的牛胚胎和胎儿上丘的发育进行了研究。大体上,在CRL为0.8厘米时首次可识别中脑,而在CRL为4.5厘米的胚胎中可清楚区分上丘。该脑区的大体特征在CRL为80.0厘米时达到成年状态。光学显微镜检查显示,在CRL为0.8厘米时开始形成层,这是由脑室区的增殖活动诱导的。直至CRL为3.4厘米时,视顶盖原基仍呈现三层模式(脑室层、中间层和边缘层),但在CRL为4.5厘米时,特定顶盖层的形成以深层和中层的起源为标志。随着在CRL为8.0厘米时第十层即视层的出现,层状模式与成年动物的特征相符。