Bono Ariño A, Piñero Fernández A, Rodríguez Vela L, Ascaso Cornago I, Allepuz Losa C, Rioja Sanz L A
Servicio de Urología, Hospital Miguel Servet, Zaragoza, España.
Arch Esp Urol. 1997 Oct;50(8):897-905.
The present study investigated the somatosensory evoked potential (SSEP) from the dorsal penile nerve and the bulbocavernosus reflex (BCR) in healthy volunteers and patients with erectile dysfunction in order to establish a model of normality and investigate the abnormal neuro-urophysiological measurements in patients with erectile dysfunction and their relationship with different factors (age, neurological disease).
30 healthy volunteers and 102 patients who had consulted for erectile dysfunction underwent neuro-urophysiological diagnostic evaluation (dorsal penile nerve SSEP and BCR). The mean age was 51.2 years (range 27 to 66).
The group of healthy volunteers showed SSEP mean latency of 46.374 ms and a BCR mean latency of 43.721 ms. Thirty-four patients (33.33%) had at least one abnormal neuro-urophysiological measurement, the SSEP were abnormal in 7 (20.58%), the BCR in 5 (14.70%) and both in 22 (64.70%). We found an increased SSEP latency and BCR latency in the patients with erectile dysfunction and with no urological disease. Comparison of the older with the younger patients was only statistically significant for increased BCR latency in patients > 60 years old.
The study revealed neuro-urophysiological abnormalities in 34 impotent patients (33.33%). The finding of abnormalities in both BCR and SSEP was the most frequent.
本研究对健康志愿者和勃起功能障碍患者的阴茎背神经体感诱发电位(SSEP)及球海绵体反射(BCR)进行了研究,以建立正常模型,并探究勃起功能障碍患者的神经-泌尿生理学测量异常及其与不同因素(年龄、神经疾病)的关系。
30名健康志愿者和102名因勃起功能障碍前来咨询的患者接受了神经-泌尿生理学诊断评估(阴茎背神经SSEP和BCR)。平均年龄为51.2岁(范围27至66岁)。
健康志愿者组的SSEP平均潜伏期为46.374毫秒,BCR平均潜伏期为43.721毫秒。34名患者(33.33%)至少有一项神经-泌尿生理学测量异常,其中7名(20.58%)SSEP异常,5名(14.70%)BCR异常,22名(64.70%)两者均异常。我们发现,无泌尿系统疾病的勃起功能障碍患者的SSEP潜伏期和BCR潜伏期增加。老年患者与年轻患者相比,仅60岁以上患者的BCR潜伏期增加具有统计学意义。
该研究揭示了34名阳痿患者(33.33%)存在神经-泌尿生理学异常。BCR和SSEP均异常最为常见。