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后颅窝手术后的小脑缄默症——两例病例报告

Cerebellar mutism after posterior fossa surgery--two case reports.

作者信息

Kai Y, Kuratsu J, Suginohara K, Marubayashi T, Ushio Y

机构信息

Department of Neurosurgery, Kumamoto University Medical School.

出版信息

Neurol Med Chir (Tokyo). 1997 Dec;37(12):929-33. doi: 10.2176/nmc.37.929.

Abstract

Two adults (aged 71 and 74 years) developed cerebellar mutism after posterior fossa surgery for a mass lesion in the superior cerebellar hemisphere or upper vermis. Histological examination showed one was a hemangioblastoma, the other a metastatic brain tumor. The tumors were totally removed via the occipital transtentorial approach. Both patients developed mutism on the 2nd postoperative day, which persisted for 3-4 weeks and was followed within 2-4 months by cerebellar dysarthria. Thereafter, their condition improved. Transient cerebellar mutism usually occurs in pediatric patients after the removal of a mass lesion in the upper vermis. Cerebellar mutism in adults is rare. The predominance of cerebellar mutism in children may be attributable to the predilection for vermian tumor and their tendency to experience personality and behavioral changes after posterior fossa surgery.

摘要

两名成年人(年龄分别为71岁和74岁)在接受后颅窝手术切除小脑上半球或上蚓部的占位性病变后出现了小脑缄默症。组织学检查显示,其中一例为血管母细胞瘤,另一例为脑转移瘤。肿瘤通过枕下经小脑幕入路被完全切除。两名患者均在术后第2天出现缄默症,持续3 - 4周,随后在2 - 4个月内出现小脑性构音障碍。此后,他们的病情有所改善。短暂性小脑缄默症通常发生在小儿患者切除上蚓部占位性病变之后。成人小脑缄默症较为罕见。儿童小脑缄默症的 predominance 可能归因于蚓部肿瘤的易发性以及他们在后颅窝手术后出现性格和行为改变的倾向。(注:原文中“predominance”翻译为“优势、突出”等词在语境中不太合适,推测此处可能是想表达“发生率较高”之类的意思,但按照要求不添加解释,保留原文词汇)

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