Shukla S K, Evans J T, Mittelman A
J Surg Oncol. 1976;8(2):99-103. doi: 10.1002/jso.2930080202.
This is a retrospective study of 14 patients with lymphosarcoma with hypersplenism. Eight patients received radiation to the spleen followed by splenectomy for recurrence of hypersplenism. Six patients underwent primary splenectomy for hypersplenism. Radiation decreases the size of the spleen but recurrence of hypersplenism is seen in an average of 8 mo. Splenectomy in these cases improves the hematological picture. Average postsplenectomy survival is 27.6 mo. Splenectomy alone in hypersplenism also improves the hematological picture. Postsplenectomy survival in this group is 13 mo. One case of primary lymphosarcoma of the spleen is reported.
这是一项对14例伴有脾功能亢进的淋巴肉瘤患者的回顾性研究。8例患者接受了脾脏放疗，随后因脾功能亢进复发而进行了脾切除术。6例患者因脾功能亢进而接受了一期脾切除术。放疗可减小脾脏大小，但平均8个月后会出现脾功能亢进复发。在这些病例中，脾切除术可改善血液学状况。脾切除术后的平均生存期为27.6个月。单纯脾切除术治疗脾功能亢进也可改善血液学状况。该组患者脾切除术后的生存期为13个月。报告了1例原发性脾脏淋巴肉瘤病例。
