Mulkey J P, Oehme F W
Comparative Toxicology Laboratories, Kansas State University, Manhattan 66506-5606, USA.
Vet Hum Toxicol. 1998 Feb;40(1):11-4.
Thallium is a highly toxic cumulative poison in humans and animals. The use of the metal as a component in ceramic superconductor material (CSM) raised concern about the health risk of CSM to children accidentally swallowing some of the CSM or to occupationally-exposed workers in the electronics industry. This study examined the biological availability of CSM by quantifying the thallium content in organs, blood and fecal matter of Sprague-Dawley rats after a single acute oral exposure to CSM and compares these values to similar thallium measurements from identical exposure to thallium sulfate. The CSM-exposed group had significantly less thallium than the thallium sulfate-exposed group in all tissues/fluids analyzed. This suggested that CSM poses a lower health risk to exposed persons than thallium sulfate.
铊对人类和动物而言是一种剧毒的累积性毒物。将该金属用作陶瓷超导材料（CSM）的一种成分，引发了人们对CSM对意外吞食部分CSM的儿童或电子行业职业暴露工人健康风险的担忧。本研究通过对斯普拉格-道利大鼠单次急性口服暴露于CSM后，对其器官、血液和粪便中的铊含量进行定量分析，研究了CSM的生物可利用性，并将这些值与相同暴露于硫酸铊后的类似铊测量值进行比较。在所有分析的组织/液体中，暴露于CSM的组的铊含量明显低于暴露于硫酸铊的组。这表明CSM对暴露人群造成的健康风险低于硫酸铊。
