Oki S, Nomura Y, Sugio Y, Young Y H
Department of Otolaryngology, Showa University, Tokyo, Japan.
J Clin Laser Med Surg. 1996 Dec;14(6):393-8. doi: 10.1089/clm.1996.14.393.
The effects of argon laser on the bony semicircular canals were studied in the guinea pig. After intraperitoneal administration of Nembutal, the bulla was opened in order to approach the lateral and posterior canals. The anterior canal was approached through the posterior fossa. The argon laser was applied through a probe which was connected to a device from HGM Medical Laser Systems. One of the three semicircular canals was irradiated one to several times by argon laser (1.0-1.5 W x 0.5 sec). Histopathologic examination of the temporal bones revealed that the semicircular duct shrank immediately after irradiation. The laser produced a charred area in the bony canal wall. The semicircular canals gradually became fibrotic and ossified and completely occluded within several weeks. Heat produced in the bony canal may be responsible for the morphologic changes. On delayed observation, the cochlea of the canal-irradiated animals showed no morphologic changes. Auditory brain stem responses were normal. Caloric stimulation using 5 ml/5 sec of ice water revealed no response in the lateral canal-irradiated animals.
在豚鼠身上研究了氩激光对骨性半规管的影响。腹腔注射戊巴比妥后,打开鼓泡以接近外侧和后半规管。通过后颅窝接近前半规管。氩激光通过连接到HGM医学激光系统设备的探头进行照射。对三个半规管中的一个用氩激光照射一至数次(1.0 - 1.5瓦×0.5秒)。颞骨的组织病理学检查显示,照射后半规管立即收缩。激光在骨管壁上产生了一个烧焦区域。半规管逐渐纤维化并骨化,在几周内完全闭塞。骨管内产生的热量可能是形态学变化的原因。延迟观察时,接受半规管照射的动物的耳蜗未显示形态学变化。听觉脑干反应正常。对接受外侧半规管照射的动物使用5毫升/5秒的冰水进行冷热试验未显示反应。