生理和肿瘤过程中的蛋白质磷酸化与去磷酸化
Protein phosphorylation and dephosphorylation in physiologic and oncologic processes.
作者信息
Patarca R
机构信息
Department of Medicine, E. M. Papper Laboratory of Clinical Immunology, University of Miami School of Medicine, FL 33160, USA.
出版信息
Crit Rev Oncog. 1996;7(5-6):343-432. doi: 10.1615/critrevoncog.v7.i5-6.20.
Abstract
Phosphorylation and dephosphorylation of proteins is an important regulatory mechanism of cell metabolism, proliferation and differentiation. The present review summarizes the known key players, their interactions, effects on physiological processes, and their role in pathology and neoplasia.
摘要
蛋白质的磷酸化和去磷酸化是细胞代谢、增殖和分化的重要调节机制。本综述总结了已知的关键参与者、它们之间的相互作用、对生理过程的影响以及它们在病理学和肿瘤形成中的作用。
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