Hoffman O, Carreres T, Sapoval M R, Auguste M C, Beyssen B M, Raynaud A C, Gaux J C
Department of Cardiovascular Radiology, Broussais Hospital, Paris, France.
J Vasc Interv Radiol. 1998 Jan-Feb;9(1 Pt 1):65-73. doi: 10.1016/s1051-0443(98)70484-1.
To report the immediate results and the clinical and angiographic outcome of percutaneous angioplasty in patients with ostial renal artery stenosis.
Retrospective review of 52 percutaneous transluminal renal angioplasty (PTRA) procedures for strictly defined ostial atherosclerotic renal artery stenosis in 50 consecutive patients, selected among 670 PTRAs performed between 1983 and 1993.
Immediate angiographic success was achieved in 30 arteries (58%) and improvement was achieved in 15 arteries (29%). The procedure was a failure in seven lesions (13%). PTRA was followed by a stent implantation in three lesions (6%). Two patients (4%) died within the first month after PTRA and a major complication occurred in seven other patients (13%). At a mean follow-up of 20.6 months, both systolic and diastolic blood pressure decreased significantly (P = .0006 and P = .0057 respectively). Renal function did not change significantly (P = .73). One patient was lost during follow-up. At angiographic control (mean, 11 months), restenosis occurred in 27% of the cases. There was no recurrence of pulmonary edema at a mean follow-up of 32 months in 50% of the 12 patients who experienced one episode or more before PTRA.
True ostial renal artery stenosis is rare and often reflects severe and multifocal atheromatous disease. In these patients, PTRA might be considered an acceptable and relatively safe treatment that improves blood pressure and stabilizes renal function.
报告经皮血管成形术治疗肾动脉开口处狭窄患者的即时结果以及临床和血管造影结果。
回顾性分析1983年至1993年间进行的670例经皮腔内肾血管成形术(PTRA)中,连续50例严格定义为肾动脉开口处动脉粥样硬化性狭窄患者的52例PTRA手术。
30条动脉(58%)实现了即时血管造影成功,15条动脉(29%)有所改善。7处病变(13%)手术失败。3处病变(6%)在PTRA后进行了支架植入。2例患者(4%)在PTRA后第一个月内死亡,另外7例患者(13%)发生了严重并发症。平均随访20.6个月时,收缩压和舒张压均显著下降(分别为P = 0.0006和P = 0.0057)。肾功能无显著变化(P = 0.73)。1例患者在随访期间失访。在血管造影复查时(平均11个月),27%的病例出现再狭窄。在PTRA前经历过一次或多次肺水肿的12例患者中,50%在平均32个月的随访中未出现肺水肿复发。
真正的肾动脉开口处狭窄很少见,常反映严重的多灶性动脉粥样硬化疾病。对于这些患者,PTRA可被视为一种可接受且相对安全的治疗方法,可改善血压并稳定肾功能。