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人卵巢静脉血浆中的双氢睾酮

Dihydrotestosterone in human ovarian venous plasma.

作者信息

Calabresi E, Fiorelli G, Forti G, Lombardi G, Pazzagli M, Dell'Acqua E, Serio M

出版信息

Acta Endocrinol (Copenh). 1976 Jun;82(2):380-7. doi: 10.1530/acta.0.0820380.

DOI:10.1530/acta.0.0820380
PMID:946925
Abstract

Androstenedione (delta), oestradiol-17beta (Oe2), 5alpha-dihydrotestosterone (DHT), progesterone (P) and testosterone (T) concentrations have been measured by radioimmunoassay in ovarian and peripheral venous blood from 15 women in the luteal phase of the cycle. The ovarian blood samples were obtained during surgical intervention from 15 ovaries containing the corpus luteum and from 5 contralateral ovaries. The mean concentration of DHT in ovarian venous blood was not higher than that found in the cubital vein. However in some cases with high concentrations of testosterone in ovarian venous blood, a small but significant DHT gradient was found.

摘要

采用放射免疫分析法测定了15名处于月经周期黄体期的女性卵巢静脉血和外周静脉血中雄烯二酮(δ)、雌二醇-17β(E2)、5α-双氢睾酮(DHT)、孕酮(P)和睾酮(T)的浓度。卵巢血样是在手术干预期间从15个含有黄体的卵巢以及5个对侧卵巢中采集的。卵巢静脉血中DHT的平均浓度不高于肘静脉血中的浓度。然而,在一些卵巢静脉血中睾酮浓度较高的病例中,发现了一个虽小但显著的DHT梯度。

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