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未经治疗的急性视神经炎后的残余症状和体征。一年随访

Residual symptoms and signs after untreated acute optic neuritis. A one-year follow-up.

作者信息

Frederiksen J L, Sørensen T L, Sellebjerg F T

机构信息

Department of Neurology, Glostrup University Hospital, University of Copenhagen, Denmark.

出版信息

Acta Ophthalmol Scand. 1997 Oct;75(5):544-7. doi: 10.1111/j.1600-0420.1997.tb00147.x.

Abstract

PURPOSE

To study the symptoms and signs one year after optic neuritis.

METHODS

Seventy population-based untreated patients, (44F, 26M; median age 35 years, range 14-48 years) were eligible for study, but the 11 bilateral cases were excluded. Among 59 patients participating in a one-year follow-up of the visual function, 58 answered a questionnaire.

RESULTS

At follow-up 59% of the patients complained of visual impairment, though 49% of these patients had a Snellen visual acuity of 6/9 or better. The affected eyes showed decreased visual acuity in 34%, decreased contrast sensitivity in 63%, an abnormal score in 40% with the Lanthony D-15 desaturated panel, and in 13% with the Ishihara test, prolonged latencies of VEP in 58%, and decreased amplitudes of VEP in 41%.

CONCLUSIONS

All tests except for VEP correlated significantly to the degree of perceived visual impairment. Subjective visual complaints and more sensitive tests than visual acuity should be used to evaluate the visual function following optic neuritis.

摘要

目的

研究视神经炎发病一年后的症状和体征。

方法

选取70例未经治疗的基于人群的患者(44例女性,26例男性;年龄中位数35岁,范围14 - 48岁)纳入研究,但排除11例双侧病例。在参与视觉功能一年随访的59例患者中,58例回答了问卷。

结果

随访时,59%的患者主诉有视力损害,不过其中49%的患者Snellen视力为6/9或更好。患眼表现为:34%视力下降,63%对比敏感度下降,使用Lanthony D - 15去饱和色盘检查时40%异常,使用石原氏色盲测试时13%异常,58%视觉诱发电位(VEP)潜伏期延长,41% VEP波幅降低。

结论

除VEP外,所有检查均与感知到的视力损害程度显著相关。评估视神经炎后的视觉功能时,应采用主观视觉主诉以及比视力更敏感的检查。

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