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发育中大鼠嗅觉上皮顶端表面的类神经元细胞。

Neuron-like cells on the apical surface of the developing rat olfactory epithelium.

作者信息

Menco B P, Jackson J E

机构信息

Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208-3520, USA.

出版信息

Neurosci Lett. 1997 Dec 19;239(2-3):117-20. doi: 10.1016/s0304-3940(97)00884-7.

DOI:10.1016/s0304-3940(97)00884-7
PMID:9469670
Abstract

Using scanning electron microscopy (SEM), we encountered a new phenomenon in developing olfactory structures. A few cells with single slender processes that sprout from their cell bodies were found lying on the surface of the developing olfactory epithelium in 15 and 16 day old rat embryos. These slender processes resemble leading processes as they often have filopodia or filopodium-like structures at their distal ends. This finding suggests a presence of a small population of olfactory epithelial cells that resemble, but need not be, neurons. Their location may reflect cell shedding, but the fact that they extend processes over the epithelial surface may also mean that the cells were caught while they were migrating.

摘要

利用扫描电子显微镜(SEM),我们在发育中的嗅觉结构中发现了一种新现象。在15和16日龄大鼠胚胎的发育中的嗅觉上皮表面,发现了一些细胞,它们从细胞体发出单个细长的突起。这些细长的突起类似于引导突起,因为它们的远端通常有丝状伪足或丝状伪足样结构。这一发现表明存在一小群类似于神经元但不一定是神经元的嗅觉上皮细胞。它们的位置可能反映了细胞脱落,但它们在上皮表面延伸突起这一事实也可能意味着这些细胞在迁移时被捕获。

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