黑头呆鱼（肥头鲦鱼，Pimephales promelas）体内萘和1,2,4-三氯苯的脂质含量及致死剂量与死亡时间的关系

Lipid content and time-to-death-dependent lethal body burdens of naphthalene and 1,2,4-trichlorobenzene in fathead minnow (Pimephales promelas).

作者信息

de Maagd P G, van de Klundert I C, van Wezel A P, Opperhuizen A, Sijm D T

机构信息

RITOX/Environmental Chemistry Group, Utrecht University, The Netherlands.

出版信息

Ecotoxicol Environ Saf. 1997 Dec;38(3):232-7. doi: 10.1006/eesa.1997.1583.

DOI:10.1006/eesa.1997.1583

PMID:9469874

Abstract

For naphthalene (NAPH) and 1,2,4-trichlorobenzene (TCBz), lethal body burdens (LBB) of 8 +/- 3.1 mmol/kg wet wt (ww) and 14 +/- 4.5 mmol/kg (ww), respectively, were determined in fathead minnow (Pimephales promelas). LBBs of both compounds were found to increase with increasing lipid content and time-to-death of fish within the same aquarium. The correlation with time-to-death suggests that besides lipid content at least one other factor causes intraspecies variation in LBBs. When intraspecies variation is excluded by comparing mean LBBs from different aquaria and exposure regimes, LBBs still vary with time-to-death. In contrast to the situation within one aquarium, between different aquaria and exposure regimes often a decrease in LBB with time-to-death is found. The present study and others indicate that LBBs can vary with time-to-death. Therefore, a time-independent LBB cannot be assumed.

摘要

对于萘（NAPH）和1,2,4 - 三氯苯（TCBz），在黑头呆鱼（肥头鲦鱼，Pimephales promelas）中分别测定出致死体内负荷（LBB）为8±3.1 mmol/kg湿重（ww）和14±4.5 mmol/kg（ww）。发现这两种化合物的LBBs均随同一水族箱内鱼的脂质含量增加和死亡时间延长而增加。与死亡时间的相关性表明，除脂质含量外，至少还有一个其他因素导致种内LBBs的变化。当通过比较来自不同水族箱和暴露方案的平均LBBs来排除种内变化时，LBBs仍随死亡时间而变化。与一个水族箱内的情况相反，在不同水族箱和暴露方案之间，经常会发现LBBs随死亡时间而降低。本研究及其他研究表明，LBBs会随死亡时间而变化。因此，不能假定存在与时间无关的LBB。