Jensen L S, Chang C H
Poult Sci. 1976 Mar;55(2):594-9. doi: 10.3382/ps.0550594.
Growth rate of Single Combe White Leghorn cockerels fed a casein-gelatin-glucose diet was significantly depressed at two weeks when 10 p.p.m. or more selenium was added to the diet. When 20% linseed meal was included in the diet, growth was not reduced with 10 p.p.m. selenium and only slightly reduced with 20 p.p.m. selenium. Including 20% soybean meal failed to modify the toxicity. Levels of 5 and 10% linseed meal were less effective in counteracting selenosis than was 20%. Fractionation studies showed that a protective factor in linseed meal was extracted by methanol and ethanol and was not destroyed by autoclaving. Ashing the ethanol extract destroyed its activity. The factor was readily extracted by chlorform:methanol (2:1) but less effectively by acetone and diethyl ether. Washed chloroform:methanol extract was inactive but the washings contained the factor. Concentrates of the factor were active at less than 1% of the dry matter of the diet. The results of these studies show that linseed meal contains a heat stable, organic, polar factor that modified selenium toxicity in the chick.
给单冠白来航公鸡饲喂酪蛋白 - 明胶 - 葡萄糖日粮时，日粮中添加百万分之十或更多的硒会在两周时显著抑制其生长速度。当日粮中包含20%的亚麻籽粕时，添加百万分之十的硒不会降低生长速度，添加百万分之二十的硒时生长仅略有降低。包含20%的豆粕未能改变毒性。5%和10%的亚麻籽粕在对抗硒中毒方面不如20%的亚麻籽粕有效。分级分离研究表明，亚麻籽粕中的一种保护因子可被甲醇和乙醇提取，且不会因高压灭菌而被破坏。将乙醇提取物灰化会破坏其活性。该因子很容易被氯仿：甲醇（2:1）提取，但丙酮和乙醚的提取效果较差。用氯仿：甲醇洗涤后的提取物无活性，但洗涤液中含有该因子。该因子的浓缩物在日粮干物质含量低于1%时仍具有活性。这些研究结果表明，亚麻籽粕含有一种热稳定的有机极性因子，可改变雏鸡对硒的毒性。
