Pavić-Sladoljev D, Oresković K
Pliva d.d., Program farmaceutike, Zagreb.
Lijec Vjesn. 1997 Jul;119(7):193-200.
The survey on outpatients compliance in the treatment of respiratory tract infections was performed in Croatia during April 1996. A total of 213 physicians, 201 adult patients, and 178 parents of sick children were polled by the appropriate questionnaires. The results have shown that in the treatment of respiratory tract infections physicians commonly prescribe thrice-daily antibiotic regimens for 8-10 days. Concerning patients' knowledge, 85% of patients deem that regularity, and 64% that duration of antibiotic administration influences treatment outcome. Over 80% of patients are compliant with once-or twice-daily regimens, but only 50% take regularly and timely drugs that are dosed every 6 or 8 hours. Common reasons for irregular taking of antibiotics are forgetfulness and dosing during sleeping. In terms of appropriate duration of antibiotic therapy, about 20% of patients usually take antibiotic for 8-10 days, 60% for 5-7 days, and 20% for < or = 4 days. It may be concluded that the patients are poorly compliant with oral antibiotics treatment.
1996年4月在克罗地亚开展了一项关于呼吸道感染门诊患者治疗依从性的调查。通过相应问卷对213名医生、201名成年患者以及178名患病儿童的家长进行了调查。结果显示,在呼吸道感染治疗中,医生通常会开出每日三次、疗程8至10天的抗生素治疗方案。关于患者的认知,85%的患者认为用药规律,64%的患者认为抗生素给药时长会影响治疗效果。超过80%的患者能遵守每日一次或两次的给药方案,但只有50%的患者能按时规律服用每6或8小时给药一次的药物。不规律服用抗生素的常见原因是忘记服药以及在睡觉时服药。在抗生素治疗的适当疗程方面,约20%的患者通常服用抗生素8至10天,60%的患者服用5至7天,20%的患者服用≤4天。可以得出结论,患者口服抗生素治疗的依从性较差。