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南非朗克洛弗地区的碘缺乏与地方性甲状腺肿

Iodine deficiency and endemic goitre in the Langkloof area of South Africa.

作者信息

Jooste P L, Weight M J, Kriek J A

机构信息

National Research Programme for Nutritional Intervention, Medical Research Council, Tygerberg, W Cape.

出版信息

S Afr Med J. 1997 Oct;87(10):1374-9.

PMID:9472252
Abstract

OBJECTIVE

To quantify the prevalence of iodine deficiency and endemic goitre in the Langkloof area.

DESIGN

A cross-sectional study.

SETTING

Four primary schools in four communities in the Langkloof.

SUBJECTS

565 primary schoolchildren from Standard 2 to Standard 5.

OUTCOME MEASURES

Clinical diagnosis of thyroid size by palpation, level of iodine in urine and drinking water samples, level of iodine in iodised salt samples from the area, percentage of households with iodised salt on the premises, and anthropometric measures of body height and weight.

RESULTS

The prevalence of endemic goitre varied from 14.3% to 30.2% in the four communities and, based on urinary iodine levels, the iodine deficiency ranged from mild to severe. Both iodised and non-iodised salt were available at the local grocery stores but only small percentages of households had iodised salt in the house. The iodine content of drinking water was low. Anthropometric indices of undernutrition indicated medium to high levels of stunting in three of the four communities, the worst being in the community with the highest goitre prevalence.

CONCLUSIONS

Endemic goitre caused by iodine deficiency is a public health problem in the Langkloof, varying in severity from mild to severe in the different communities. The impact of mandatory iodisation of table salt, introduced at the end of 1995, needs to be assessed in these communities.

摘要

目的

量化朗克洛弗地区碘缺乏病和地方性甲状腺肿的患病率。

设计

一项横断面研究。

地点

朗克洛弗四个社区的四所小学。

研究对象

565名来自二年级至五年级的小学生。

观察指标

通过触诊对甲状腺大小进行临床诊断、尿液和饮用水样本中的碘含量、该地区碘盐样本中的碘含量、家中有碘盐的家庭百分比,以及身高和体重的人体测量指标。

结果

四个社区的地方性甲状腺肿患病率在14.3%至30.2%之间,根据尿碘水平,碘缺乏程度从轻度到重度不等。当地杂货店既有碘盐也有非碘盐出售,但只有一小部分家庭家中有碘盐。饮用水中的碘含量较低。营养不良的人体测量指标表明,四个社区中有三个社区存在中度至高度发育迟缓情况,甲状腺肿患病率最高的社区情况最差。

结论

碘缺乏导致的地方性甲状腺肿是朗克洛弗地区的一个公共卫生问题,在不同社区的严重程度从轻度到重度不等。1995年底实行的食盐强制加碘措施对这些社区的影响需要进行评估。

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