Bognar M, Blake W, Agudelo C
Internal Medicine Department, VA Medical Center, Emory University Hospital, Atlanta, Georgia, USA.
Am J Med Sci. 1998 Feb;315(2):133-5. doi: 10.1097/00000441-199802000-00010.
Chronic recurrent multifocal osteomyelitis (CRMO) was first described by Giedion in 1972 as a self-limited relapsing noninfectious inflammatory condition usually affecting children and adolescents. The association of CRMO with psoriasis, palmoplantar pustulosis, and SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) has been described. In this case report, we present a 49-year-old man with CRMO coexisting with Crohn's disease. To our knowledge, this is the first report of CRMO with Crohn's disease without the presence of pustular skin lesions or other features of SAPHO syndrome.
慢性复发性多灶性骨髓炎（CRMO）于1972年由吉迪恩首次描述，是一种通常影响儿童和青少年的自限性复发性非感染性炎症性疾病。CRMO与银屑病、掌跖脓疱病和SAPHO综合征（滑膜炎、痤疮、脓疱病、骨质增生和骨炎）的关联已被描述。在本病例报告中，我们介绍了一名49岁患有CRMO并伴有克罗恩病的男性。据我们所知，这是首例CRMO合并克罗恩病且无脓疱性皮肤病变或SAPHO综合征其他特征的报告。
