Thomas R, Jacob P, Braganza A, Mermoud A, Muliyil J
Schell Eye Hospital, Christian Medical College, Vellore, India.
Indian J Ophthalmol. 1997 Mar;45(1):37-41.
A retrospective review of 154 trabeculectomies with releasable sutures was performed to assess the effect of suture release on intraocular pressure (IOP) at various postoperative periods. Release of the suture was necessary in 38% of cases. The immediate reduction in IOP was significant (p < 0.01) when the suture was released during the first three postoperative weeks. Seventy percent of eyes had a reduction in IOP more than 5 mmHg if released within the first week compared to 20% after the third week. With suture release after the third postoperative week, there was no clinically significant decrease in IOP. The decrease in IOP was similar in eyes undergoing trabeculectomy alone or when cataract extraction through a separate corneal incision was undertaken simultaneously. The period during which release of suture was effective was not prolonged by use of antimetabolites. Complications included a typical windshield-wiper keratopathy (18 eyes), failure to release the suture (13 eyes), epithelial abrasion (6 eyes) and a sub-conjunctival bleed (1 eye).
对154例采用可松解缝线的小梁切除术进行回顾性研究，以评估缝线松解在术后不同时期对眼压（IOP）的影响。38%的病例需要松解缝线。如果在术后前三周内松解缝线，眼压立即降低显著（p<0.01）。与第三周后松解缝线的20%的眼相比，70%的眼如果在第一周内松解缝线，眼压降低超过5mmHg。术后第三周后松解缝线，眼压无临床显著下降。单纯小梁切除术或同时通过单独的角膜切口进行白内障摘除术的眼，眼压降低情况相似。使用抗代谢药物并未延长缝线松解有效的时间。并发症包括典型的擦窗样角膜病变（18只眼）、未能松解缝线（13只眼）、上皮擦伤（6只眼）和结膜下出血（1只眼）。
