Watanabe H, Enjoji M, Imai T
Cancer. 1976 Jul;38(1):232-43. doi: 10.1002/1097-0142(197607)38:1<232::aid-cncr2820380135>3.0.co;2-4.
A type of gastric carcinoma was specified under the designation carcinoma with lymphoid stroma. Grossly, this carcinoma was characterized by clear circumscription, usually with a central ulceration. A histologic feature distinguishing this carcinoma was the presence of a nondesmoplastic stroma infiltrated uniformly with an abundance of lymphocytes and plasma cells throughout the entire area of the tumor. Sparse population of less pleomorphic cancer cell nests of thin trabecular, microalveolar, or primitive tubular pattern widely separated by the intervening stroma was another feature peculiar to this tumor. Carcinoma of this type was found in 4% of a total of 1041 cases of gastric carcinoma removed surgically. A high survival rate was noted among the patients undergoing surgery for this carcinoma. A proposal was made on the separate classification of this tumor from common gastric carcinomas.
一种胃癌被指定为伴有淋巴样间质的癌。大体上，这种癌的特征是边界清晰，通常有中央溃疡。区分这种癌的组织学特征是存在一种非促纤维增生性间质，在肿瘤的整个区域均匀地浸润着大量淋巴细胞和浆细胞。另一个该肿瘤特有的特征是癌细胞巢数量稀少，细胞异型性较小，呈细小梁状、微腺泡状或原始管状结构，被其间质广泛分隔。在1041例手术切除的胃癌病例中，这种类型的癌占4%。接受这种癌手术的患者生存率较高。有人提议将这种肿瘤与常见胃癌分开分类。
