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一项针对在初级保健诊所就诊的哮喘患者比较呼气峰值流速和症状自我管理计划的随机试验。

A randomized trial comparing peak expiratory flow and symptom self-management plans for patients with asthma attending a primary care clinic.

作者信息

Turner M O, Taylor D, Bennett R, Fitzgerald J M

机构信息

Department of Medicine, University of British Columbia, Vancouver, Canada.

出版信息

Am J Respir Crit Care Med. 1998 Feb;157(2):540-6. doi: 10.1164/ajrccm.157.2.9703060.

Abstract

Great emphasis is placed on educating asthmatics to use action plans to achieve better control of symptoms. The use of peak flow meters (PFM) has been recommended as an important part of self-management plans. We studied 92 (47 F) adult patients with asthma in a primary care setting to compare the effectiveness of action plans using either peak flow monitoring or symptoms to guide self-management. Each patient was instructed in the use of the action plan in the context of a 6-mo asthma education program taught by a nurse. Patients were already using inhaled corticosteroids or were newly prescribed corticosteroids by their family physician. Forty-four patients were randomized to the PFM group and 48 to the symptoms group. Spirometry, symptom scores, quality of life, medication use, and measures of health care utilization and morbidity (emergency department visits, hospitalizations, unscheduled doctor visits, and days lost from work or school) were recorded at baseline and throughout the study period. PC20 methacholine was measured at the first and at the final visits. There were significant improvements within groups for FEV1, symptoms score, PC20 methacholine, and quality of life, but no between-group differences. A significant shift from higher to lower daily use of beta-agonists (p < 0.008 for both groups) and significant shifts to higher daily doses of inhaled steroids (p < 0.001) occurred in each group. Adherence to the self-management plans was only 65% in the PFM group and 52% in the symptoms group. Outcomes for health care utilization were similar except for fewer patients making unscheduled doctor visits within the PFM group. Our findings show that education, regular follow-up, and an action plan are effective in improving asthma control and quality of life, but the routine use of PFM to guide interventions is not the only way to accomplish these objectives.

摘要

重点大力放在教育哮喘患者使用行动计划以更好地控制症状上。使用峰流速仪(PFM)已被推荐为自我管理计划的重要组成部分。我们在初级保健机构中研究了92名(47名女性)成年哮喘患者,以比较使用峰流速监测或症状来指导自我管理的行动计划的有效性。每位患者在由护士讲授的为期6个月的哮喘教育项目中接受了行动计划使用的指导。患者已在使用吸入性糖皮质激素或由其家庭医生新开具了糖皮质激素。44名患者被随机分配到PFM组,48名患者被分配到症状组。在基线和整个研究期间记录了肺活量测定、症状评分、生活质量、药物使用以及医疗保健利用和发病率的指标(急诊就诊、住院、非预约医生就诊以及工作或学校缺勤天数)。在首次和最后一次就诊时测量了乙酰甲胆碱激发试验的PC20。各组内FEV1、症状评分、PC20乙酰甲胆碱和生活质量均有显著改善,但组间无差异。每组中β受体激动剂的每日使用量均从较高水平显著下降(两组均p < 0.008),吸入性糖皮质激素的每日剂量均显著增加(p < 0.001)。PFM组的自我管理计划依从率仅为65%,症状组为52%。除了PFM组中非预约医生就诊的患者较少外,医疗保健利用的结果相似。我们的研究结果表明,教育、定期随访和行动计划在改善哮喘控制和生活质量方面是有效的,但常规使用PFM来指导干预并不是实现这些目标的唯一途径。

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