Christie P, Claffey N, Renvert S
School of Dental Science, Trinity College, Dublin, Ireland.
J Clin Periodontol. 1998 Jan;25(1):15-23. doi: 10.1111/j.1600-051x.1998.tb02358.x.
The aim of the present study was to evaluate a 0.2% chlorhexidine mouthrinse following the non-surgical treatment of advanced human periodontitis in the absence of a structured mechanical oral hygiene regimen. 10 patients and a total of 1483 sites were used. Recordings for plaque, bleeding, pocket depth and attachment levels were made at baseline and at 3, 6, 9, and 12 months. Debridement was performed under local anaesthesia. No instruction or reinforcement in mechanical oral hygiene procedures was given at any time. However, at each visit the patients were instructed in the 2x daily use of 0.2% chlorhexidine mouthwash. The plaque indices, scored as % of sites with removable deposits, showed negligible improvement from baseline scores of 80%-100% for all categories of initial probing depth. Mean bleeding score was reduced to 10-20% irrespective of initial probing pocket depth, site location or tooth surface location. Sites > or = 7 mm at baseline demonstrated a reduction in mean probing pocket depth of 3.9 mm and a gain in mean probing attachment level of 2.5 mm. Moderately deep sites (4-6.5 mm) demonstrated a reduction in mean probing pocket depth of 2 mm and a gain in mean probing attachment level of 0.8 mm. Shallow sites (< or = 3.5 mm) demonstrated a reduction in mean probing pocket depth of 0.5 mm and a loss in mean probing attachment level of 0.2 mm. Site-specific attachment level analysis demonstrated that over 80% of losing sites were shallow with low bleeding frequency, indicating that the loss of attachment may have occurred for reasons other than inflammatory periodontal disease. The results indicate that chlorhexidine can be used as an adjunct to inadequate mechanical oral hygiene over an observation period of 1 year.
本研究的目的是在缺乏结构化机械口腔卫生方案的情况下,评估0.2%氯己定漱口水用于晚期人类牙周炎非手术治疗的效果。研究使用了10名患者,共1483个位点。在基线以及3、6、9和12个月时记录菌斑、出血情况、牙周袋深度和附着水平。在局部麻醉下进行清创。在任何时候都未给予机械口腔卫生程序方面的指导或强化措施。然而,每次就诊时都指导患者每天使用两次0.2%氯己定漱口水。菌斑指数以有可去除沉积物的位点百分比计分,所有初始探诊深度类别的基线分数为80%-100%,改善可忽略不计。无论初始探诊牙周袋深度、位点位置或牙面位置如何,平均出血分数均降至10%-20%。基线时≥7mm的位点平均探诊牙周袋深度减少3.9mm,平均探诊附着水平增加2.5mm。中度深度位点(4-6.5mm)平均探诊牙周袋深度减少2mm,平均探诊附着水平增加0.8mm。浅位点(≤3.5mm)平均探诊牙周袋深度减少0.5mm,平均探诊附着水平降低0.2mm。位点特异性附着水平分析表明,超过80%的附着丧失位点较浅且出血频率低,这表明附着丧失可能是由炎症性牙周病以外的原因引起的。结果表明,在1年的观察期内,氯己定可作为机械口腔卫生不足的辅助手段。