Jacobi E, Karges H E, Heimburger N
Dtsch Med Wochenschr. 1976 Aug 13;101(33):1220-2. doi: 10.1055/s-0028-1104245.
A simple method for the routine determination of plasminogen using the coagulation time is described. 0.2 ml of plasminogen reagent and 0.1 ml of sample plasma, prediluted 1:200, are incubated for 3 minutes at 37 degrees C. 0.05 ml of diluted test thrombin are then added and the coagulation time is measured. It is converted into percent of normal using a standard curve. The test correlates with an immunological method in healthy probands (r = 0.96). Initial measurements in 160 patients show that knowledge of the plasminogen titre may also be of interest outside the problems of haemostasis.
描述了一种使用凝血时间常规测定纤溶酶原的简单方法。将0.2 ml纤溶酶原试剂和0.1 ml预稀释1:200的样本血浆在37℃孵育3分钟。然后加入0.05 ml稀释的测试凝血酶并测量凝血时间。使用标准曲线将其换算为正常百分比。该测试与健康受试者的免疫方法相关(r = 0.96)。对160例患者的初步测量表明,了解纤溶酶原滴度在止血问题之外可能也有意义。