Girndt J, Kramer P, Quellhorst E, Held K, Bohle A, Scheler F
Dtsch Med Wochenschr. 1976 Aug 20;101(34):1246-51. doi: 10.1055/s-0028-1104250.
Five personal cases and many reports in the literature demonstrate the not rare development of hypertension after oral contraceptives or an increase of an existing hypertension. In addition, the drug may also cause vascular changes in the kidneys with development of benign or malignant nephrosclerosis, similar to the increased risk of thrombo-embolic complications of the venous-arterial system. It is, therefore, necessary to check the blood pressure of women on oral contraceptive and, if hypertension exists or develops, discontinue these drugs.
五例个人病例以及文献中的许多报道表明,口服避孕药后高血压的发生并不罕见,或者会使原有高血压加重。此外,该药物还可能导致肾脏血管发生变化,引发良性或恶性肾硬化,这类似于静脉 - 动脉系统血栓栓塞并发症风险的增加。因此,有必要对服用口服避孕药的女性进行血压检查,如果存在高血压或血压升高,应停用这些药物。