Ferreira L A, Lima F L, dos Anjos M do R, Costa J M
Departamento de Patologia da Faculdade de Medicina da Universidade Federal do Maranhão, São Luis, Brasil.
Rev Soc Bras Med Trop. 1998 Jan-Feb;31(1):89-93. doi: 10.1590/s0037-86821998000100011.
The involvement of the central nervous system in the Schistosomiasis mansoni is uncommon and in the literature exist few reports in relation this occurrence in the brain, in that the schistosoma eggs, usually promote a granulomatous reaction that remember an expansive tumour. A patient, male sex, from São Vicente de Ferrer (MA), 27 years old, had a tumour in the cerebellum, that had surgical therapy. Later histological studies of the cerebellar material of the patient, demonstrated an extensive granulomatous reaction around schistosoma eggs. The granulomatous reaction present different stages of evolution, since degenerative necrosis to organization granulomatous reaction. This is the first report from Maranhão (Brazil). The evolution of the patient was characterized for incoordination of members and trembling.
曼氏血吸虫病累及中枢神经系统的情况并不常见,文献中关于脑部出现这种情况的报道很少,因为血吸虫卵通常会引发一种类似扩张性肿瘤的肉芽肿反应。一名来自圣维森特·德费雷尔(马拉尼昂州)的27岁男性患者,小脑长有肿瘤,并接受了手术治疗。后来对该患者小脑组织的组织学研究表明,在血吸虫卵周围出现了广泛的肉芽肿反应。肉芽肿反应呈现出从退行性坏死到肉芽肿组织形成的不同演变阶段。这是来自巴西马拉尼昂州的首例报告。该患者的病情发展表现为肢体不协调和震颤。