Rost A, Kneppenberg U, Rost P
Helv Chir Acta. 1976 Jul;43(3):271-8.
Both in a control group and in 154 patients with malignant tumors of the urogenital tract in the serum- and urinary levels of the carcinoembryonic antigen (CEA) have been ascertained by a radioimmunoassay. Serum-CEA-values lay above normal range in 71%, and urinary CEA-levels exceeded it in 46%. Only in the case of the carcinoma of the bladder a correlation was found between the CEA-curves and the clinical findings following tumor therapy. Up to the present, the CEA-test cannot be recommended as a universal screening method, but may be useful means for diagnostics and case controls, above all, with regard to the carcinoma of the bladder.
在对照组以及154例泌尿生殖道恶性肿瘤患者中,通过放射免疫测定法测定了癌胚抗原(CEA)的血清和尿液水平。血清CEA值在71%的患者中高于正常范围,尿液CEA水平在46%的患者中超过正常范围。仅在膀胱癌病例中,发现CEA曲线与肿瘤治疗后的临床结果之间存在相关性。目前,CEA检测不能作为一种通用的筛查方法推荐,但对于诊断和病例对照可能是有用的手段,尤其是对于膀胱癌。