Shabalkin I P
N.N.Blokhin Center for Cancer Research, Russian Academy of Medical Sciences, Moscow.
Vopr Onkol. 1997;43(6):632-8.
Cytophotometric findings point to a feedback link between tumor influence and remote organs and tissues in a tumor-bearing body, an important factor being whether tumor cells are located to the right or left of the modal class of normal cells of an organ. It is also important that the functional activity pattern of tumor cells genome match that of normal organ cells (Kfagen's ratio) and the number of tumor cells does not exceed that of normal cells by more than 33%.
细胞光度测定结果表明,在荷瘤机体中肿瘤影响与远处器官和组织之间存在反馈联系,一个重要因素是肿瘤细胞位于器官正常细胞众数类别的右侧还是左侧。同样重要的是,肿瘤细胞基因组的功能活性模式与正常器官细胞的功能活性模式相匹配(克法根比率),并且肿瘤细胞数量不超过正常细胞数量的33%以上。