翻译保真度：易出错与超精确核糖体

Translational fidelity: error-prone versus hyper-accurate ribosomes.

作者信息

von Ahsen U

机构信息

Research Institute of Molecular Pathology, Vienna, Austria.

出版信息

Chem Biol. 1998 Jan;5(1):R3-6. doi: 10.1016/s1074-5521(98)90080-1.

DOI:10.1016/s1074-5521(98)90080-1

PMID:9479473

Abstract

Decoding mRNA is a multistep process involving the RNA and protein components of the ribosome, and external factors; little is known about the mechanism, however. New evidence suggests that a central region in small ribosomal RNA switches between two helices in translation to maintain translational fidelity.

摘要

解码信使核糖核酸（mRNA）是一个涉及核糖体的RNA和蛋白质成分以及外部因素的多步骤过程；然而，人们对其机制知之甚少。新证据表明，小核糖体RNA中的一个中心区域在翻译过程中会在两个螺旋之间切换，以维持翻译保真度。