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[蛋白A免疫吸附治疗难治性自身免疫性血小板减少症患者]

[Protein A immunoadsorption treatment of patients with refractory autoimmune thrombopenia].

作者信息

Petersen N, Bremer K, Hammad-Zulfughari D, Kemper J, Grüntjes-Prinsen G, Hansmann E

机构信息

Institut für Blutspendewesen, Städtische Kliniken Dortmund, Deutschland.

出版信息

Beitr Infusionsther Transfusionsmed. 1994;32:366-9.

PMID:9480126
Abstract

Eight patients with chronic immunothrombocytopenia (ITP) who had failed at least one alternative therapy were treated with extracorporeal immunoadsorption. Two of the 8 patients responded to the treatment with a stable increase in platelet counts, but both of them had to be continuously treated with corticosteroids. Side effects of the treatment with extracorporeal immunoadsorption were musculoskeletal pain, nausea, vomiting, tachycardia, purpura, fatigue, and others.

摘要

8例慢性免疫性血小板减少症(ITP)患者,至少一种替代疗法治疗失败后,接受了体外免疫吸附治疗。8例患者中有2例对治疗有反应,血小板计数稳定增加,但两人都必须持续接受皮质类固醇治疗。体外免疫吸附治疗的副作用包括肌肉骨骼疼痛、恶心、呕吐、心动过速、紫癜、疲劳等。

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