Koscielny J, Kiesewetter H, Jung F, Pindur G, Jakobs K, Wenzel E
Abteilung für Klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, Homburg, Deutschland.
Beitr Infusionsther Transfusionsmed. 1994;32:492-4.
Clinically, only patients treated with HES in stage of autologous blood sampling benefited significantly. Two patients showed adverse effects. The peri- and postoperative course was comparable. In the NaCl group one of the patients received homologous erythrocyte concentrates. None of the patients died pre-, peri- or postoperatively. 40% of the cardiosurgical patients could be considered for autologous blood donation. Isovolemic hemodilution with HES 200/0.5 10% was a suitable and safe measure in preoperative blood sampling. Physical exercise test should be performed before and after autologous blood donation. A reduced exercise tolerance suggests to stop autologous blood donation.
临床上，仅在自体采血阶段接受羟乙基淀粉（HES）治疗的患者受益显著。两名患者出现了不良反应。围手术期和术后过程相当。在生理盐水组中，有一名患者接受了异体红细胞浓缩物。没有患者在术前、术中和术后死亡。40%的心脏外科手术患者可考虑进行自体献血。使用10%的HES 200/0.5进行等容血液稀释是术前采血的一种合适且安全的措施。自体献血前后应进行体能运动测试。运动耐力下降表明应停止自体献血。
