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[通过在含葡萄糖-腺嘌呤-磷酸盐和柠檬酸盐的溶液中洗涤来恢复自体血液的活力]

[Rejuvenation of autologous blood preserved by washing in glucose- adenine- phosphate- and citrate-containing solution].

作者信息

Matthes G, Richter E, Tofoté U, Pawlow I, Kucera W, Lerche D

机构信息

Institut für Transfusionsmedizin, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Deutschland.

出版信息

Beitr Infusionsther Transfusionsmed. 1994;32:498-501.

PMID:9480151
Abstract

Outdated red cell concentrates (RCC-SAGM) were washed with a chloride-free, glucose-adenine-phosphate-citrate preservation solution. After resuspension of the red cells in this solution a hypothermic storage for additional 63 days was performed. Quality parameters (2,3-DPG, glucose, lactose, free hemoglobin, pH, chloride, pO50, shape quality index, filtration index) of the preserved red blood cells became normal within 7-11 days after the rejuvenation procedure. The data prove that a rejuvenation of outdated blood by a simple washing procedure allows a post-storage time of 21 days.

摘要

将过期的红细胞浓缩液(RCC-SAGM)用不含氯的葡萄糖-腺嘌呤-磷酸盐-柠檬酸盐保存液洗涤。在将红细胞重悬于该溶液后,进行了额外63天的低温储存。在复苏程序后的7-11天内,保存的红细胞的质量参数(2,3-二磷酸甘油酸、葡萄糖、乳糖、游离血红蛋白、pH值、氯、P50、形状质量指数、过滤指数)恢复正常。数据证明,通过简单的洗涤程序使过期血液复苏可实现21天的储存后使用时间。

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