Dmitriev S G
Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.
Genetika. 1997 Nov;33(11):1589-92.
Frequencies of chromosomal aberrations were estimated in the bone marrow of two background small rodent species, the bank vole (Clethrionomys glareolus) and the house mouse (Mus musculus) from the middle (Chapaevsk, Samarskaya oblast) and lower (Astrakhanskaya oblast) Volga regions. The majority of chromosomal aberrations were chromatid deletions. In the studied species, cytogenetic disturbances were most prevalent in areas where the anthropogenic environmental pollution was maximum. The lowest frequencies of disturbances were observed in the control areas, where the environmental pollution was insignificant. Thus, anthropogenic exposure caused disturbances of cytogenetic homeostasis in different small rodents living in different regions.
在来自伏尔加河中游地区(萨马拉州恰帕耶夫斯克)和下游地区(阿斯特拉罕州)的两种野生小型啮齿动物——小林姬鼠(Clethrionomys glareolus)和家鼠(Mus musculus)的骨髓中,对染色体畸变频率进行了估算。大多数染色体畸变是染色单体缺失。在所研究的物种中,细胞遗传学紊乱在人为环境污染最严重的地区最为普遍。在环境污染微不足道的对照区域,观察到的紊乱频率最低。因此,人为暴露导致生活在不同地区的不同小型啮齿动物的细胞遗传稳态受到干扰。