Kosowski K, Heczko P, Karczewska E
I Katedry i Kliniki Chirurgii Ogólnej i Gastroenterologicznej, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1997;54(7-8):551-3.
Prophylactic antibiotic regimen (gentamicin, clindamycin) was assessed in a group of 104 patients operated electively on biliary lithiasis (cholecysto- and choledocholithiasis). Antibiotic prophylaxis was performed in group of 20 patients, in 6 of them antibiotics were continued postoperatively. Intraoperatively antibiotics were given in a group of 20 patients--curative treatment. Control group consisted of 58 patients. We concluded that "one shoot" antibiotic therapy is valuable in controlling of wound infections. But the most effective method of reducing local septic complications rate combines prophylaxis with prolonged antibiotic administration.
在一组104例择期接受胆石症（胆囊结石和胆总管结石）手术的患者中评估了预防性抗生素方案（庆大霉素、克林霉素）。20例患者进行了抗生素预防，其中6例术后继续使用抗生素。20例患者术中给予抗生素——进行治疗性处理。对照组由58例患者组成。我们得出结论，“单次”抗生素治疗对于控制伤口感染是有价值的。但降低局部感染并发症发生率的最有效方法是将预防与延长抗生素给药相结合。
