Chipeva V A, Ivanova I V, Gocheva B
National Collection of Microorganisms and Cell Cultures, Sofia, Bulgaria.
Antibiot Khimioter. 1997;42(12):3-5.
Antibiotic activity, aminotransferase activity and composition of intracellular amino acids in low and high potent variants of Streptomyces hygroscopicus 155 were studied. The data of the study are indicative of some general regularities characteristic of amino acid metabolism in actinomycetes: an increased pool of the main aminodonor amino acids (alanine, asparaginic and glutaminic acids) and an increased activity of aminotransferases in the cultures of both the variants when grown in media with readily assimilable nitrogen sources.
对吸水链霉菌155低活性和高活性变体的抗生素活性、转氨酶活性及细胞内氨基酸组成进行了研究。研究数据表明了放线菌氨基酸代谢的一些普遍规律:当在含有易同化氮源的培养基中生长时,两种变体培养物中主要氨基供体氨基酸(丙氨酸、天冬氨酸和谷氨酸)的库增加,转氨酶活性增强。