Yoshioka T, Kobayashi C, Suda H, Sasaki T
Department of Endodontics, Faculty of Dentistry, Tokyo Medical and Dental University, Japan.
Dentomaxillofac Radiol. 1997 Sep;26(5):286-94. doi: 10.1038/sj.dmfr.4600259.
To elucidate the accuracy in vitro of quantitative digital subtraction for direct digital dental radiography using a commercially available image analysis system.
Images were corrected first for dark current and sensitivity variation among pixels of the CCD sensor (first correction), and corrected further for interimage variations due to the variations in exposure conditions (second correction). A copper stepwedge with six steps was used in the second correction. Three corrected images derived from three original images at each different exposure time were examined to confirm the reliability of the second correction. Correlation between bone mineral content and pixel value was assessed in subtracted images of an artificial bone phantom.
The first and second corrections significantly improved the intra- and inter-image variation respectively. The second corrected images obtained at three different exposure times showed almost the identical grey levels. An original image was transformed to a copper equivalent image with a high reliability by our original method. The pixel value in the subtracted image between two copper equivalent images of a bone phantom was linearly related to the bone mineral content. There was a slight overestimate at lower pixel values but it was accurate at higher pixel values.
Quantification of digital subtraction using this method is sufficiently reliable for its application to clinical practice to be evaluated.
使用商用图像分析系统阐明直接数字化牙科X线摄影术中定量数字减影的体外准确性。
首先对图像进行暗电流校正以及电荷耦合器件(CCD)传感器各像素间灵敏度变化的校正(第一次校正),然后针对由于曝光条件变化导致的图像间差异进一步校正(第二次校正)。第二次校正中使用了具有六级的铜阶梯楔形块。检查了在每个不同曝光时间从三张原始图像得到的三张校正图像,以确认第二次校正的可靠性。在人工骨模型的减影图像中评估骨矿物质含量与像素值之间的相关性。
第一次和第二次校正分别显著改善了图像内和图像间的差异。在三个不同曝光时间获得的第二次校正图像显示出几乎相同的灰度级。通过我们的原始方法,一张原始图像被可靠地转换为等效铜图像。骨模型的两张等效铜图像之间的减影图像中的像素值与骨矿物质含量呈线性相关。在较低像素值时有轻微高估,但在较高像素值时是准确的。
使用该方法进行数字减影定量对于评估其在临床实践中的应用而言足够可靠。