口服前列环素（PGI2）类似物贝拉普罗钠对一名原发性肺动脉高压患者的有益血流动力学效应——病例报告

Beneficial hemodynamic effects of oral prostacyclin (PGI2) analogue, beraprost sodium, on a patient with primary pulmonary hypertension--a case report.

作者信息

Hashida H, Hamada M, Shigematsu Y, Ikeda S, Kuwahara T, Kawakami H, Hara Y, Kodama K, Kohara K, Hiwada K

机构信息

Second Department of Internal Medicine, Ehime University School of Medicine, Onsen-gun, Japan.

出版信息

Angiology. 1998 Feb;49(2):161-4. doi: 10.1177/000331979804900210.

DOI:10.1177/000331979804900210

PMID:9482517

Abstract

A 65-year-old woman was admitted to our hospital because of exertional dyspnea in 1987. A diagnosis of primary pulmonary hypertension was confirmed by right heart catheterization. She had received conventional therapy in the outpatient clinic. She was readmitted with the deterioration of exertional dyspnea in 1995. Stabilization of pulmonary hemodynamics, while not achieved with conventional therapy, was achieved with additive administration of an oral prostacyclin (PGI2) analogue, beraprost sodium.

摘要

一名65岁女性于1987年因劳力性呼吸困难入院。经右心导管检查确诊为原发性肺动脉高压。她在门诊接受了常规治疗。1995年，她因劳力性呼吸困难加重再次入院。常规治疗未能实现肺血流动力学稳定，但加用口服前列环素（PGI2）类似物贝拉普罗钠后实现了稳定。