Saji T, Ozawa Y, Ishikita T, Matsuura H, Matsuo N
Department of Pediatrics, Toho University, Tokyo, Japan.
Am J Cardiol. 1996 Jul 15;78(2):244-7. doi: 10.1016/s0002-9149(96)90408-7.
In 4 patients with primary pulmonary hypertension, there was a -24% +/- 20% decrease in pulmonary vascular resistance, a significant increase of cardiac index by +27 +/- 14% in all 4 patients; a -15 +/- 12% decrease in pulmonary artery pressure in 3 patients; and in 3 patients with 12% secondary pulmonary hypertension, there was a -24 +/- 14% decrease in pulmonary vascular resistance. Beraprost appears to be effective as a new pulmonary vasodilative agent.
在4例原发性肺动脉高压患者中，肺血管阻力下降了24%±20%，所有4例患者的心指数显著增加了27±14%；3例患者的肺动脉压下降了15±12%；在3例继发性肺动脉高压患者中，肺血管阻力下降了24±14%。贝拉普罗斯作为一种新型肺血管扩张剂似乎是有效的。
