Sudo E, Ohga E, Matsuse T, Teramoto S, Nagase T, Katayama H, Takizawa H, Tanaka M, Kikuchi N, Kakurai S, Fukuchi Y, Ouchi Y
Department of Geriatrics, Faculty of Medicine, University of Tokyo.
Nihon Ronen Igakkai Zasshi. 1997 Nov;34(11):929-34. doi: 10.3143/geriatrics.34.929.
It has been suggested that pulmonary rehabilitation compined with inspiratory muscle training (IMT) might improve pulmonary function and respiratory muscle strength in elderly patients with chronic obstructive pulmonary disease (COPD). To test this hypothesis, inspiratory muscle strength (PImax), expiratory muscle strength (PEmax) and resting pulmonary function were measured in 13 elderly patients with COPD (aged 70.3 +/- 2.7 years). Inspiratory muscle training (IMT) was performed for 15 min twice a day, using a pressure threshold device, for a total of 12 weeks. The inspiratory threshold was set at 15% of maximal inspiratory pressure (PImax) for each individual. Pulmonary rehabilitation was performed for 12-h sessions over a 12-week period. Patients with COPD were assigned randomly to two groups: pulmonary rehabilitation combined with IMT (group A) (n = 7), and conventional pulmonary rehabilitation only (group B) (n = 6). Functional residual capacity (FRC) decreased significantly from 4.3 +/- 0.4 L at baseline to 3.9 +/- 0.4 L after rehabilitation (p < 0.01), Vp significantly increased from 4.6 +/- 0.8 L/sec at baseline to 5.1 +/- 0.7 L/sec after rehabilitation (p < 0.05) and the PImax increased significantly from 51.5 +/- 5.4 cmH2O at baseline to 80.9 +/- 7.0 cmH2O after rehabilitation (p < 0.02) in group A. However, these variables did not change in group B. There was no improvement in the 10-minutes walking distance of group A, but there was a significant increase in that of group B. It can be concluded that pulmonary rehabilitation combined with IMT improves pulmonary function and inspiratory muscle strength in elderly patients with COPD.
有人提出,肺康复结合吸气肌训练(IMT)可能会改善老年慢性阻塞性肺疾病(COPD)患者的肺功能和呼吸肌力量。为了验证这一假设,对13例老年COPD患者(年龄70.3±2.7岁)测量了吸气肌力量(PImax)、呼气肌力量(PEmax)和静息肺功能。使用压力阈值装置,每天进行两次15分钟的吸气肌训练,共12周。每个个体的吸气阈值设定为最大吸气压力(PImax)的15%。在12周的时间内进行12小时的肺康复治疗。COPD患者被随机分为两组:肺康复结合IMT组(A组)(n = 7)和仅进行传统肺康复组(B组)(n = 6)。A组的功能残气量(FRC)从基线时的4.3±0.4 L显著下降至康复后的3.9±0.4 L(p < 0.01),Vp从基线时的4.6±0.8 L/秒显著增加至康复后的5.1±0.7 L/秒(p < 0.05),PImax从基线时的51.5±5.4 cmH2O显著增加至康复后的80.9±7.0 cmH2O(p < 0.02)。然而,B组这些变量没有变化。A组的10分钟步行距离没有改善,但B组有显著增加。可以得出结论,肺康复结合IMT可改善老年COPD患者的肺功能和吸气肌力量。