Treib J, Dobler G, Haass A, von Blohn W, Strittmatter M, Pindur G, Froesner G, Schimrigk K
Department of Neurology, University Hospital of Saarland, Homburg, Germany.
Neurology. 1998 Feb;50(2):509-11. doi: 10.1212/wnl.50.2.509.
Systematic studies of a possible human neuropathogenicity of the Erve virus have not yet been carried out. In a randomized, blind study 166 patients with viral encephalitis, 46 patients with cerebral hemorrhage, 72 patients with "thunderclap" headache, and 205 healthy blood donors were examined by indirect immunofluorescence for Erve virus antibodies. None of the patients with encephalitis, two patients with cerebral hemorrhage (4.3%), 10 patients with thunderclap headache (13.9%; p < 0.0001), and two blood donors (1.0%) exhibited antibodies against the Erve virus. These results suggest a human pathogenicity of the Erve virus for the first time.
尚未对埃尔夫病毒可能的人类神经致病性进行系统研究。在一项随机、盲法研究中,通过间接免疫荧光法检测了166例病毒性脑炎患者、46例脑出血患者、72例“霹雳样”头痛患者和205名健康献血者体内的埃尔夫病毒抗体。脑炎患者中无人、2例脑出血患者(4.3%)、10例霹雳样头痛患者(13.9%;p<0.0001)和2名献血者(