Girardi L N, Coselli J S
Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Ann Thorac Surg. 1998 Feb;65(2):491-5. doi: 10.1016/s0003-4975(97)01300-3.
Reports on octogenarians undergoing coronary revascularization, valve replacement, and abdominal aneurysmorrhaphy demonstrate little increase in operative risk during elective procedures. However, the mortality in this group of patients increases rapidly when urgent or emergent procedures are performed. We analyzed the outcome of patients in their ninth decade of life undergoing repair of thoracoabdominal aortic aneurysms.
A retrospective review of 39 consecutive octogenarians undergoing repair of thoracoabdominal aortic aneurysms.
Thirty-nine of the past 900 patients with thoracoabdominal aortic aneurysms (5.2%) repaired by us were between the ages of 80 and 89 years. The median age was 84 years with a male-to-female ratio of 1:3. Two of 39 patients (5%) had acute type III dissections, and the remainder had chronic aneurysms. Twelve patients had Crawford extent I aneurysms, whereas 7, 10, and 10 patients were extent II, III, and IV, respectively. The overall in-hospital mortality was 10.3% (4 of 39 patients). Major postoperative complications included paraperesis/paraplegia, 5% (n = 2); renal failure, 18% (n = 7) including hemodialysis in 3 patients; stroke, 5% (n = 2); myocardial infarction or arrhythmia, 18% (n = 7); and respiratory insufficiency, 36% (n = 14) including 4 patients requiring tracheostomy. A univariate analysis of perioperative risk factors was performed using the Fisher's exact test. The need for hemodialysis (p = 0.035), a tracheostomy (p = 0.0001), or a perioperative myocardial infarction (p < 0.001) significantly increased the risk of death.
Repair of thoracoabdominal aortic aneurysms in octogenarians can be performed with acceptable morbidity and mortality. However, survival decreases dramatically with even single system organ failure. An extended period of recovery is usually required in these elderly, high-risk patients.
关于八旬老人接受冠状动脉血运重建、瓣膜置换和腹主动脉瘤修补术的报告显示,择期手术期间手术风险增加不多。然而,当进行急诊或紧急手术时,这组患者的死亡率会迅速上升。我们分析了90岁左右接受胸腹主动脉瘤修复术患者的预后情况。
对39例连续接受胸腹主动脉瘤修复术的八旬老人进行回顾性研究。
在我们过去修复的900例胸腹主动脉瘤患者中,39例(5.2%)年龄在80至89岁之间。中位年龄为84岁,男女比例为1:3。39例患者中有2例(5%)患有急性III型夹层,其余为慢性动脉瘤。12例患者为Crawford I型动脉瘤,而分别有7例、10例和10例患者为II型、III型和IV型。总体住院死亡率为10.3%(39例患者中的4例)。主要术后并发症包括轻瘫/截瘫,5%(n = 2);肾衰竭,18%(n = 7),其中3例患者需要血液透析;中风,5%(n = 2);心肌梗死或心律失常,18%(n = 7);呼吸功能不全,36%(n = 14),其中4例患者需要气管切开术。使用Fisher精确检验对围手术期危险因素进行单因素分析。需要血液透析(p = 0.035)、气管切开术(p = 0.0001)或围手术期心肌梗死(p < 0.001)会显著增加死亡风险。
八旬老人胸腹主动脉瘤修复术可以在可接受的发病率和死亡率下进行。然而,即使单一系统器官衰竭,生存率也会急剧下降。这些老年高危患者通常需要较长的恢复时间。